Vash the Stampede is a gunman on the run with a 60 billion double dollar bounty on his head which has made it difficult for him to go anywhere without being chased and shot at. Because of the bounty, every town he ever visit ends up being destroyed because of his pursuers, but miraculously no one ever gets killed. Meryl and Milly are two insurance agents that have been sent to find Vash the Stampede and keep him under surveillance so no more damage is caused. Meryl, who leads the pair, can't believe that the man they have met can possibly be the legendary gunman. This spikey haired, gangly, and blonde young man is extremely friendly, a pacifist, hates blood and suicide, absolutely loves donuts, and is a dork and a crybaby... there is no way he could be Vash the Stampede, a notorious outlaw. However, there's more to Vash than just smiles and donuts; a dark past that he would like to leave behind is hounding him, and some people are pursuing him for other reasons than the bounty.